It flows initially southeastwardly along the boundaries of Grant, LaSalle, and Rapides parishes, before turning east-northeastwardly into LaSalle Parish through Catahoula Lake, which is bordered by the Catahoula National Wildlife Refuge.

In the twentieth century the waste from the oil production and exploration damaged the riparian lands in LaSalle Parish.

"[6]) The Little River, as measured at the USGS station at Rochelle, LA, has a mean annual discharge of 2,260 cubic feet per second.

This portion of the river flows through a mixed oak-gum bottomland forest interspersed with stands of bald cypress.

[8] Sixty prehistoric Native American archaeological sites have been identified along this stretch of the river.