11322217353ENSG00000141524ENSMUSG00000025572Q7Z403Q7TN60NM_001375353NM_001375354NM_001374596NM_145439NM_181321NP_001362282NP_001362283NP_001361525NP_663414Transmembrane channel-like protein 6 is a protein that in humans is encoded by the TMC6 gene.

[5][6] In vivo, TMC6 and its homolog TMC8, interact and form a complex with the zinc transporter 1 (SLC30A1) and localize mostly to the endoplasmic reticulum, but also to the nuclear membrane and Golgi apparatus.

[7] Inactivating mutations in TMC6 or TMC8 have been implicated as the genetic cause of the rare skin disorder epidermodysplasia verruciformis,[7] which is characterized by abnormal susceptibility to human papillomaviruses (HPVs) of the skin resulting in the growth of scaly macules and papules, particularly on the hands and feet.

This protein-related article is a stub.

You can help Wikipedia by expanding it.