[20] In addition to regular, honors, and Advanced Placement classes, the curriculum includes numerous electives in humanities, business, visual arts, music, drama, family and consumer science, and technology education.

[26] The East Brunswick High School Bears[3] compete in the Greater Middlesex Conference, which is comprised of public and private high schools in the Middlesex County area and operates under the supervision of the New Jersey State Interscholastic Athletic Association.

[28] The football team competes in Division 5C of the Big Central Football Conference, which includes 60 public and private high schools in Hunterdon, Middlesex, Somerset, Union and Warren counties, which are broken down into 10 divisions by size and location.

[33] A goal scored in the last minute of play in regulation gave the 1986 team a 1–0 win again Westfield in the Group IV championship game and a 25–0 record for the season.

[36] The Bears won five consecutive Greater Middlesex Conference Tournament titles, including a 2–1 victory over Old Bridge in 2007 and a 3–0 win over Bishop Ahr in 2008.

[38][39] The team won the inaugural Tournament of Champions in 1992 against runner-up Newark Academy, and were ToC finalists in 2004, 2021, and 2022.

[42] The boys' bowling team won the overall state championship in 1997, and the Group IV title in 2017 and 2018.

[45] The team won the 2007 NJSIAA South Jersey sectional championship with a 25–19, 31–29 victory over Southern Regional High School.

[47] The girls basketball team won the Group IV state championship in 1999, defeating Columbia High School by a score of 63–57 in the tournament final[48][49] and advanced to the Tournament of Champions as the third seed, beating sixth-seed Paterson Catholic High School 58–43 in the first round before falling to number-two West Morris Mendham High School 71–40 in the semifinals to finish the season with a 28–4 record.

[50][51] The football team won the Central Jersey Group IV state sectional championships in 2004 and 2009.

[52] The team won their first playoff-era title with a 17–12 win against Jackson High School in the finals of the Central Jersey Group IV tournament.

[57][58] The girls' tennis team won the Greater Middlesex Conference title for nine consecutive years from 2006 to 2014.

[62] On October 7, 2005, shortly after being informed by then-Superintendent of Schools Jo Ann Magistro that he would not be permitted to join his football team in prayer as he had done in the past and that some parents had complained about the prayers, East Brunswick High School coach Marcus Borden resigned from his position.

"[63] The East Brunswick football team lost its game in a shutout on the day Borden resigned.

Following Borden's resignation, nearly 100 players, parents, and coaches arrived at his house on a rainy day pleading for his return.

[65] He filed a lawsuit against the district on November 23 alleging that it was violating his constitutional rights; lawyer Ronald Riccio represented Borden.

[67] However, this decision was overturned on April 15, 2008, by a unanimous decision in the United States Court of Appeals for the Third Circuit, in which Judge D. Michael Fisher concluded that "a reasonable observer would conclude that he is continuing to endorse religion when he bows his head during the pre-meal grace and takes a knee with his team in the locker room while they pray.

[69] In February 2019, a student from EBHS forged a letter on social media and in a bathroom at the school that had the signature of Superintendent Victor Valeski on it.

The female white student was criminally charged and arrested with simple assault and harassment after an investigation by the East Brunswick Police Department and the Middlesex County Prosecutor's Office.

The district responded by halting the distribution of yearbooks, initiating an investigation, and planning to reprint affected pages.