The school is located on County Route 516 in Old Bridge Township, however, it is assigned a Matawan mailing address.

Dr. James Hickey was hired in 2003 and he oversaw a $26.8 million high school construction project that was completed in September 2005.

For his work in transforming Old Bridge High School, Dr. Hickey was recognized as the New Jersey Principal of the Year in 2009.

[15] The Old Bridge High School Knights[1] compete in the Greater Middlesex Conference, which is comprised of public and private high schools located in the Middlesex County area and operates under the supervision of the New Jersey State Interscholastic Athletic Association.

[20] The 1998 team won the Handchen Cup with a 5–4 win against Toms River High School East in the championship game played at South Mountain Arena.

[25] In 2015, the Knights football team made a second appearance in the Central Jersey Group V title game, falling to an undefeated South Brunswick High School by a score of 42–0 in the tournament final.

The two schools will continue to have a "Battle of Route 18" rivalry game that will be played as part of the regular schedule.

[32] In 2018, the team won the school's first Tournament of Champions title in any sport with a win in the finals against Southern Regional.

[33] The team repeated as state champion in 2019 with a win in three sets in the finals against Fair Lawn High School.

[34] In June 2022, the team lost the first set and came back to win 2–1 against Southern to earn their fourth consecutive ToC title.

Their first competition against Eastern Christian High School aired on MSG Varsity on February 3, 2011, with Old Bridge winning 290–240.

In 2005, the OBHSMK gained a Silver-medal finalist position in the Tournament of Bands' Group III 2005 Atlantic Coast Championship with their show Wild Knights.

[36] Their show Metamorphosis was ranked fourth place in the same competition in 2006 with a score of 95.00, making them a Gold-medal finalist.

In the 2010 season, the Marching Knights placed sixth in group IV with the theme Requiem for a Knightmare.

Recently in the 2011 season with the show In Motion the Marching Knights ranked sixth in group III and tied for Best Music.