[6] The first South Brunswick High School, located at the corner of Major Road and Kingston Lane, was dedicated in October 1960 with a crowd of 800 in attendance.

The South Brunswick High School Vikings[3] compete in the Greater Middlesex Conference, which is comprised of public and private high schools in the Middlesex County area, and operates under the supervision of the New Jersey State Interscholastic Athletic Association (NJSIAA).

[24] The 1968 boys' basketball team won the Group I state title with a 50–49 win against an East Rutherford High School team coached by Dick Vitale in the final game of the tournament played in front of 12,000 spectators at Convention Hall in Atlantic City.

[25][26] The baseball team won the Group II state title in 1980 with a 3–1 defeat of runner-up Garfield High School in the championship game played at Mercer County Park.

South Brunswick then went on to be seeded #20 in the NJSIAA Public A Tournament and lost by a score of 3–0 in the first round to Tenafly High School.

[34] The 2012 football team won the Central Jersey Group V sectional title, beating Manalapan High School by a score of 33–22.

[35] The 2015 football team won the Central Jersey Group V sectional title, defeating Old Bridge High School in the tournament final by a score of 42–0.

[36] In 2017, the team won its third championship in program history with an 18–14 win against top-seeded Manalapan High School in the final of the Central Jersey Group V state sectional tournament, played at High Point Solutions Stadium; South Brunswick finished the season with an 11–1 record, defeating a Manalapan team that had been undefeated heading into the game.

[41] The boys indoor / winter track team won the Group IV state championship in 2014 and 2020.

[42] The Viking Marching Band was the Group VI New Jersey state champions in the four consecutive seasons from 2013 through 2016 and again from 2018 through 2022.