5708993685ENSG00000198018ENSMUSG00000025192Q9NQZ7Q3TCT4NM_020354NM_001349962NM_001349963NM_053103NP_065087NP_001336891NP_001336892NP_444333Ectonucleoside triphosphate diphosphohydrolase 7 is a protein that in humans is encoded by the ENTPD7 gene.

[5] This gene encodes a purine-converting ectoenzyme which belongs to the ecto-nucleoside triphosphate diphosphohydrolase (E-NTPDase) family.

The encoded protein hydrolyzes extracellular nucleoside triphosphates (UTP, GTP, and CTP) to nucleoside monophosphates as part of a purinergic signaling pathway.

This gene affects oxidative stress as well as DNA damage and is a mediator of senescence.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.