The start was not great until she was noticed and signed by Women Management's Milan division at the age of 17 years, later, VIVA in Paris in 2006.
[6] The following month, she featured in her first Vogue Paris editorial, shot by Katja Rahlwes, followed by another in February 2007 by Mark Segal.
She featured prominently in the 2008 Versace Fragrance, Marc O'Polo, Giuseppe Zanotti and Eres Paris print campaigns.
[9] Vilkevičiūtė has graced the pages of many fashion magazines around the world including covers for Marie Claire in August 2007 and May 2008, Vogue in Germany (August 2009) and Russia (May 2007), Numéro in September 2008, Allure, and i-D. During the Spring/Summer 2009 season she walked over 35 runways for some of the world's top designers, such as Chloe, Shiatzy Chen, Chanel, Stella McCartney, Givenchy, Yves Saint Laurent, Zac Posen, and Dolce & Gabbana, and later participated in the Victoria's Secret Fashion Show 2009, in the sections "All Aboard" and "Enchanted Forest".
She was photographed by both Terry Richardson and Patrick Demarchelier as the face of Yves Saint Laurent cosmetics and Blumarine respectively.
She also participated in the Victoria's Secret Fashion Show 2010, in the segments "Country Girls" (where she wore "Angel" wings for the first time) and "PINK Planet".
Took her own self-portrait for the new Rag & Bone Do-It-Yourself ad campaign spring 2011 along with models Sasha Pivovarova, Abbey Lee Kershaw, Candice Swanepoel, Karolína Kurková and Lily Aldridge.
[13] In mid-2013 she became the new face of Bulgari Omnia Crystalline Fragrance and she appeared in the Fall campaign ads of Juicy Couture.
In November 2014 she was on the cover of Vogue Spain[18] and the magazine 032C which fashion director is Rihanna's personal wardrobe stylist Mel Ottenberg.
She sums up the spirit of the fragrance and perfectly embodies the Paradiso woman, a bold and utterly feminine creature who irradiates her sophisticated glamour without being afraid to assert her natural seductiveness.