Elemenes are a group of closely related natural chemical compounds found in a variety of plants.
The elemenes, which include α-, β-, γ-, and δ-elemene, are structural isomers of each other and are classified as sesquiterpenes.
[5] Experiments performed in vitro show that β-elemene acts as a Rho kinase inhibitor,[6] and has anti-proliferative effects toward some cancer cell types,[7][8][9][10] indicating the possibility of its use in chemotherapy.
Clinical trials in China have been conducted in which benefits for cancer treatment have been reported, and both liposome injection and oral emulsion forms of β-elemene have been approved by the China Food and Drug Administration (CFDA) as an adjuvant therapy for use in the treatment of various cancers.
[13] A Cochrane Review of the available literature concluded that "there is no evidence from randomised controlled trials to confirm or refute the effectiveness of elemene as a treatment for lung cancer".