All the camphor-derived sunscreens dissipate the photon energy by cis-trans isomerisation.

This low quantum yield means that other photochemical processes are also occurring.

[2] Studies have raised the issue that enzacamene acts as an endocrine disruptor.

[3] In addition, there is some evidence that enzacamene may suppress the pituitary-thyroid axis, leading to hypothyroidism.

It is not approved for use in the United States by the Food and Drug Administration and it is not permitted in Japan nor in Denmark.