Epirus (/ɪˈpaɪrəs/ ih-PY-rəs; Greek: Ήπειρος, romanized: Ípiros, [ˈi.pi.ros]) is a traditional geographic and modern administrative region in northwestern Greece.

It is part of the wider historical region of Epirus, which overlaps modern Albania and Greece but lies mostly within Greek territory.

In the east, the Pindus Mountains that form the spine of mainland Greece separate Epirus from Macedonia and Thessaly.

The Epirus Region (Περιφέρεια Ηπείρου, Periféria Ipírou), as it is currently defined, was established in the 1987 administrative reform and was divided into prefectures (νομοί, nomí), which were further subdivided into municipalities (δήμοι, dhími).

Sheep and goat pastoralism has always been an important activity in the region (Epirus provides more than 45% of meat to the Greek market), but there seems to be a decline in recent years.

Tobacco is grown around Ioannina, and there is also some farming and fishing, but most of the area's food must be imported from more fertile regions of Greece.

[citation needed] The gross domestic product (GDP) of the region was €4.1 billion in 2018, accounting for 2.2% of Greek economic output.

In the past, the coastal region of Thesprotia was also home to a Cham Albanian minority, whose number did not exceed 25,000 in the 1940s, alongside the local Greeks.