The epitaph sits on the pier directly opposite to the Tomb of Ferdinand van den Eynde in the church of Santa Maria dell'Anima in Rome.

[2][3] Vrijburgh was a young Netherlandish nobleman from Alkmaar,[4][2] who, like Ferdinand van den Eynde, was part of the Flemish community of expatriates in Rome.

Vryburch was a Protestant, but his executors managed to get him buried in the church by promising that a beautiful white marble monument would be erected therein.

[2] The administration of Santa Maria dell'Anima granted permission for the installation of the epitaph on the pier above Vryburch's grave in October 1629.

For this monument, Duquesnoy innovatively abandoned architectural frameworking, supplying just a cornice to support the coat of arms, and applying it onto an existing pier.