The Escambray Mountains (Spanish: Sierra del Escambray) are a mountain range in the central region of Cuba, in the provinces of Sancti Spíritus, Cienfuegos and Villa Clara.

The Escambray Mountains are located in the south-central region of the island, extending about 80 kilometers (50 mi) from east to west, and 80 kilometers (50 mi) from north to south.

[1] Their highest peak, Pico San Juan, rises to 960 m (3,150 ft)[citation needed] above sea level.

Topes de Collantes is a nature reserve park established in the south-eastern ranges of Escambray Mountains, protecting and showcasing caves, rivers, waterfalls, and canyons.

The Valley de los Ingenios is developed at the south-eastern foot of the mountains, and is a UNESCO World Heritage Site.