Benefitting from the flat route along the Neckar, the work went forward quickly and Eßlingen station was opened to traffic on 20 November 1845.

Due to the geographical location in the valley between the Filder plateau and Schurwald range, there was no question of it becoming a railway junction.

The numerous old factory buildings in the western part of Esslingen still bear witness to the industrialisation in the late 19th and early 20th century.

In 1852 the Royal Württemberg State Railways (Königlich Württembergische Staats-Eisenbahnen, KWStE), built a second track on the Fils Valley line between Cannstatt and Plochingen.

The depot premises at 2 Bahnhofsplatz 1899 is obliquely across from the post office that was built in the neo-Gothic style in 1901 and demolished in 2001.

At the beginning of the 20th century a new railway was proposed to relieve the busy Fils Valley line, especially of freight traffic.

The interurban tramway linked the communities on the Filder plateau, Nellingen and Denkendorf with Esslingen.

From 14 October 1931, the Fils Valley line between Stuttgart Hauptbahnhof and Esslingen was made four-track.

Construction of the first single-storey station building in 1846 was probably led by George Morlok to a design by Michael Knoll.

Knoll's design was in a simple style and a slim, eight-axis construction with a gable roof.

Therefore, the state railway built a magnificent new entrance building in response to the otherwise frugal station.

[5] For the design of the entrance portal in the centre of the middle section, the architect was probably inspired by a Roman triumphal arch.

The Württemberg coat of arms surrounded by oak leaves and laurels is clearly visible above the entrance.