In the WTCR touring car series, he was the most successful driver in terms of race wins and was overall runner-up in 2019.

He performed well in his début year, finishing tied on 28 points in seventh place with compatriot and fellow rookie José María López.

[4] The Argentine government has previously provided financial support to compatriot José María López's attempts to enter Formula One.

For 2011, Guerrieri went to the United States with the ultimate goal of racing in the IndyCar Series, starting with Indy Lights.

In 2012, he again finished second in the championship behind his teammate Tristan Vautier, taking three wins, including the Indianapolis 500 support race.

[6] In 2013, Guerrieri switched to the Argentinian touring car series Turismo Carretera to drive a Dodge for Oil Competición.

[8] Guerrieri was successful on his first appearance as he finished the main race in sixth and scored the fastest lap of all during the weekend.

With three rounds remaining in the season, the Honda factory squad signed him to replace the injured Tiago Monteiro.

He then took pole position and main race victory in the final round at Qatar, ending up fourth in the drivers' standings.

[11] Guerrieri won four times again in 2020, breaking the record for most wins in WTCR, and finished fourth in the drivers' cup.

[13] Guerrieri joined the FIA TCR World Tour in 2024 with the GOAT Racing Honda team.