It was circumscribed in 2014 by Alfredo Vizzini and colleagues,[1] following a number of molecular studies that outlined a new phylogenetic framework for Boletaceae and revealed the genus Boletus in its traditional circumscription to be polyphyletic.

[2][3] However, due to lack of sufficient sequences, Wu and colleagues (2016) were reluctant to accept the newly proposed genus and considered it a synonym of Butyriboletus.

[4] Following additional phylogenetic sequencing and morphological analyses, Exsudoporus was clearly resolved as a monophyletic, homogenous and independent genus that is sister to Butyriboletus.

[5][6] Species of Exsudoporus are united by the tendency of their pores to exude yellowish droplets, hence the generic epithet.

[1] Other distinctive features separating Exsudoporus from its sister-genus Butyriboletus, include the reddish-orange colour of their pores and the distinctly elongated, often 'sculpted' (raised) reticulation on the stipe.