FKBP14 is a gene which codes for a structural protein named FKBP prolyl isomerase 14.
Procollagens are collagen precursors located in the extracellular matrix that give tissues elasticity, strength, and support.
FKBP prolyl isomerase 14 may also be involved in altering other factors in the extracellular matrix.
[3] This condition is characterized by a high range of joint movement, muscle atrophy, curved spine, and delicate cardiovascular vessels.
These symptoms are brought about by a loss of the protein which results in a disruption of endoplasmic reticulum activities and extracellular matrix organization.