It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.

It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors.

This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines.

Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy.

This may prove significant for the development of new Alzheimer's drugs and for detecting the disease before the onset of clinical symptoms.