ADAM2

251511495ENSG00000104755ENSG00000276286ENSMUSG00000022039Q99965Q60718NM_001278113NM_001278114NM_001464NM_009618NP_001265042NP_001265043NP_001455NP_033748Disintegrin and metalloproteinase domain-containing protein 2 or Beta-fertilin[5] is an enzyme that in humans is encoded by the ADAM2 gene.

[6][7][8] This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family.

Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell–cell and cell–matrix interactions, including fertilization, muscle development, and neurogenesis.

This member is a subunit of an integral sperm membrane heterodimer glycoprotein called fertilin, which plays an important role in sperm-egg interactions.

This article on a gene on human chromosome 8 is a stub.