Influenced by the works of Michelangelo, Rotblatt-Amrany developed an artistic interest in the human figure at a time in which that study was not favored in academia.
As part of her studies, Rotblatt-Amrany dissected cadavers at the Indian Valley campus in a program intended for medical students.
In 1985, she traveled to Perugia in Italy as part of a program offered by Boston University, drawing from life and experimenting with stone.
Switching to Santoli's Studio, she devoted several months to the creation of a large bas-relief on a one-ton block of rose-colored slate from Assisi.
They received a commission to create a bronze statue of basketball player Michael Jordan at Chicago's United Center.
In 2002, Rotblatt-Amrany completed her largest project of the decade; Veterans Memorial Park (2002), a nine-acre site in Munster, Indiana.
The project comprised six vignettes that included bronze sculptures, bas reliefs, laser-engraved images, and found object art.
[3] Other notable works of the 2000s were: Rotblatt-Amrany helped create The Julia Foundation, a non-profit organization dedicated to establishing a sculpture garden in historic Fort Sheridan in Lake County, Illinois.