Florence station is a train station in Florence, South Carolina, United States served by Amtrak.

It is currently served by the Palmetto and Silver Meteor routes, and is a service stop for the Auto Train.

Both station buildings are owned by McLeod Health which uses the previous station as an office building for the hospital network.

In 2018, Amtrak updated the signage at the station to be ADA compliant; additional improvements are to be finished in 2026[2] The station's platforms and tracks are owned by CSX Transportation.

This South Carolina train station-related article is a stub.