State Road 453 (SR 453), part of the Wekiva Parkway system, is a controlled-access toll road built and maintained by the Central Florida Expressway Authority (CFX).

SR 453 heads northwest–southeast from interchange 39 on SR 429 to a loop interchange with SR 46 near Mount Dora as a spur route of SR 429.

There is a toll plaza between the Lake County line and the SR 46 interchange.

There are no planned intermediate exits.

[2] SR 453 opened on March 31, 2018.