The current alignment of SR 582 is Fowler Avenue just south of the northern city limit of Tampa and Temple Terrace from Florida Avenue (U.S. Route 41 Business (US 41 Bus.

It is the primary road to access of University of South Florida (50th Street, the former State Road 582B and now County Road 582B, forms the eastern boundary of the campus; Fletcher Avenue, the former State Road 582A that was once a segment of SR 579, forms the northern boundary).

The road is named after Tampa civil rights activist Cody Fowler's mother Maud Fowler.

[citation needed] Motorists overshooting the western terminus of SR 582 travel westward along Country Club Drive 1.4 miles (2.3 km) to a T-intersection with Armenia Avenue on the western Tampa city limit, near Carrollwood; travelers overshooting the eastern terminus of SR 582 follow US 301/SR 41 near Clarkwild and toward Thonotosassa, where County Road 582 continues eastward (on Knights-Griffin Road) toward Lakeland.

SR 582 formerly extended west to Tarpon Springs and east to Lakeland.