State Road 583 (SR 583) is a 6-mile-long (10 km), north–south highway that travels from Tampa to Temple Terrace in Hillsborough County, Florida.

SR 583's southern terminus is at U.S. Route 41 (US 41) only 0.14 miles (0.23 km) away from an intersection with Interstate 4 in Tampa.

The roadway then continues north passing over SR 574 before intersecting US 92 which provides easy access to US 301 which does not intersect SR 583.

SR 583 then continues northward to Temple Terrace, Florida where it intersects the eastern terminus of State Road 580 and then terminates at SR 582 where the roadway continues north as 56th Street and County Road 583 (CR 583) to intersect CR 582A.

The entire route is in Hillsborough County.