Nike designed Flywire with inspiration from a suspension bridge, where many cables provide support.

Nike adapts Vectran fibers, which are produced by Kuraray, into embroidery threads, before use in the shoe.

Vectran is lightweight, flexible, and high in tensile strength, the stress at which material deforms (five times stronger than steel[3]), which makes it an ideal component for synthetic fibers.

[4] Due to the Vectran fibers, shoes containing Nike Flywire weigh as little as 93 grams, "approximately the weight of a Snickers bar with a bite missing.

The athletics shoes were debuted at the 2007 World Championships at Osaka, while the rest made their first appearance at the 2008 Summer Olympics, in Beijing, China, though all are now available for consumer purchase.