Fonsecaea compacta

[7][8] Carrion & Emmons reported the presence of phialides in F. compacta, which were described as being typical of those formed by Phialophora verrucosa.

[1] At one time or another, F. compacta had been placed in other genera, including, Phialophora, Hormodendrum, Acrotheca, Phialoconidiophora, Rhinocladiella or Trichosporium.

[1] Confusion surrounding F. pedrosoi and F. compacta has resulted from their polymorphic nature, in that they may form more than one type of conidia arrangement within a single culture.

[9] Evaluation of different isolates confirms the genus Fonsecaea is most logical, as characterized by their complex heads of conidia.

[9] In 2004, it was reported that based on sequences of the internal transcribed spacer (ITS) region, 39 strains of Fonsecaea spp.

[1] Some authors maintain that F. compacta and F. pedrosoi are separate species given small differences in morphology of conidiophores and conidia.

[12] In 2004, scientists from the University of Chiba in Japan found that there is no difference in subunit ribosomal DNA D1/D2 domain sequence between F. pedrosoi and F. compacta, which may indicate that the latter is merely a morphological variation of the first.

[9] Colonies on potato dextrose agar are slow growing, velvety to woolly, and olive to olivaceous black in color.

[citation needed] A large number of cases have been reported from Madagascar in Africa, Brazil and Japan.

[2] The five main causal fungi of chromoblastomycosis are F. compacta, F. pedrosoi, Phialophora verrucosa, Exophiala dermatitidis and Cladophialophora carrionii.

[citation needed] A Puerto Rican case in which the disease was confined to an upper limb and the lesions consisted of extensive, diffuse, even areas of infiltration with some papillomata on the hand and without tumors or nodules was confirmed to be caused by F.

[19] Increased cases are seen in agricultural workers such as adult male farmers and laborers, whose occupation brings them into close contact with soil, are mainly affected.

[17] The Fonsecaea species have been reported to be recoverable from environmental sources and therefore the disease is considered to be of traumatic origin.

[4] Nevertheless, the precise natural niche of both F. compacta has remained uncertain and hence it is unclear where and how symptomatic patients have acquired their infection.

[17] Early stages of treatment for minor chromoblastomycosis cases involve surgical excision, electrodesiccation.

[19] F. compacta and F. pedrosoi are less susceptible to antifungal treatments so cure rates are lower compared to other agents of the disease.