Fort Du Bus was a Dutch administrative and trading post established in 1828 on Triton Bay on the southwest coast of New Guinea, in the current Indonesian regency of Kaimana, West Papua.

Intended to counter British encroachment, it was the first European settlement in the region; it was abandoned in 1835, due to the unhealthy climate and attacks by natives.

[1] On December 31, 1827 a royal authorization was issued, and on April 21, 1828 a small expedition led by Lieutenant Jan Jacob Steenboom, with two ships, the corvette Triton and the schooner Iris, left Ambon to search for a suitable location for a settlement.

[4][5] The settlement carried on a brisk trade with the coastal Asmat people and the Papuans of the interior, as well as Ceramese traders who arrived in roofed-over, 15-to-30-foot (4.6 to 9.1 m) long prahus.

In 1839 the French explorer Jules Dumont d'Urville visited the site and found an avenue of coconut palms, a lemon grove, and a few remains of buildings.