Francisco J. Quintana (born April 30, 1974) is an Argentinean-American immunologist and neuroscientist, and Professor of Neurology at Harvard Medical School.

[3] Dr. Quintana joined Brigham and Women's Hospital and Harvard Medical School as a postdoctoral fellow in 2005 where he was advised by Dr. Howard L.

[7] Quintana's research investigates signaling pathways that control the immune response and neurodegeneration, with the ultimate goal of identifying novel therapeutic targets and biomarkers for immune-mediated disorders.

[8] Dr. Quintana's work identified important roles for the transcription factor AHR in the control of inflammation driven adaptive and innate immune cells.

*Quintana, F.J., *Jin, H., Burns, E.J., Nadeau, M., Yeste, A., Kumar, D., Rangachari, M., Zhu, C., Xiao, S., Seavitt, J., Georgopoulos, K. & Kuchroo, V.K.

Mascanfroni, I.D., Yeste, A., Vieira, S.M., Burns, E.J., Patel, B., Sloma, I., Wu, Y., Mayo, L., Efroni, S., Kuchroo, V.K., Robson, S.C. & Quintana, F.J. IL-27 acts on dendritic cells to suppress the T-cell response and autoimmunity by inducing ENTPD1 (CD39) expression.

Yeste, A., Mascanfroni, I.D., Nadeau, M., Burns, E.J., Tukpah, A.M., Santiago, A., Wu, C., Patel, B., Kumar, D. & Quintana, F.J. IL-21 induces IL-22 production in CD4+ T cells.

Mayo L, Trauger S.A., Blain M., Nadeau M., Patel B., Alvarez J.I., Mascanfroni I.D., Yeste A., Kivisäkk P., Kallas K., Ellezam B., Bakshi R., Prat A., Antel J.P., Weiner H.L.

Mascanfroni ID, Takenaka M.C., Yeste A., Patel B., Wu Y., Kenison J., Siddiqui S., Basso A.S., Otterbein L.E., Pardoll D.M., Pan F., Priel A., Clish C.B., Robson S.C. & Quintana F.J. Metabolic control of Tr1 cell differentiation by AHR and HIF1-α.

Farez, M.F., Mascanfroni, I.D., Méndez-Huergo, S., Yeste, A., Murugaiyan, G., Garo, L.P., Balbuena Aguirre, M.E., Patel, B., Ysrraelit, M.C., Zhu, C., Kuchroo, V.K., Rabinovich, G.A., *Quintana, F.J. & *Correale, J. Melatonin contributes to the seasonality of multiple sclerosis relapses.

Yeste, A., Takenaka, M.C., Mascanfroni, I.D., Nadeau, M., Kenison, J.E., Patel, B., Tukpah, A.M., Babon, J.A., DeNicola, M., Kent, S.C., Pozo, D., & Quintana, F.J. (2016).

Rothhammer, V., Mascanfroni, I.D., Bunse, L., Takenaka, M.C., Kenison, J.E., Mayo, L., Chao, C.C., Patel, B., Yan, R., Blain, M., Alvarez, J.I., Kébir, H., Anandasabapathy, N., Izquierdo, G., Jung, S., Obholzer, N., Pochet, N., Clish, C.B., Prinz, M., Prat, A., Antel, J.

Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.

Rothhammer V., Borucki D.M., Tjon E.C., Takenaka M.C., Chao C.C., Ardura-Fabregat A., de Lima K.A., Gutiérrez-Vázquez C., Hewson P., Staszewski O., Blain M., Healy L., Neziraj T., Borio M., Wheeler M., Dragin L.L., Laplaud D.A., Antel J., Alvarez J.I., Prinz M. & Quintana F.J. Microglial control of astrocytes in response to microbial metabolites.

Takenaka M.C., Gabriely G., Rothhammer V., Mascanfroni I.D., Wheeler M.A., Chao C.C., Gutiérrez-Vázquez C., Kenison J., Tjon E.C., Barroso A., Vandeventer T., Alves de Lima K., Rothweiler S., Ghannam S., Zandee S., Healy L., Sherr D., Farez M. F., Pratt A., Antel J., Reardon D.A., Zhang H., Robson S.C., Getz G., Weiner H.L.

Wheeler M.A., Jaronen M., Covacu R., Zandee S.E.J., Scalisi G., Rothhammer V., Tjon E.C., Chao C.C., Kenison J.E., Blain M., Rao V.T.S., Hewson P., Barroso A., Gutiérrez-Vázquez C., Prat A., Antel J.P., Hauser R. & Quintana F.J. Environmental control of astrocyte pathogenic activities in CNS inflammation.

Chao C.C., Gutiérrez-Vázquez C., Rothhammer V., Mayo L., Wheeler M.A., Tjon E.C., Zandee S.E.J., Blain M., Alves de Lima K., Takenaka M.C., Pacheco J.A., Hewson P., Liu L., Sanmarco L.M., Borucki D.M., Lipof G.Z., Trauger S.A., Clish C., Antel J., Prat A.

Wheeler, M. A., Clark, I.C., Tjon, E. C., Li, Z., Zandee, S.E.J., Couturier, C.P., Watson, B.R., Scalisi, G., Alkwai, S., Rothhammer, V., Rotem, A., Heyman, J.A., Thaploo, S., Sanmarco, L.M., Ragoussis, J., Weitz, D. A., Petrecca, K., Moffitt, J.R., Becher, B., Antel, J.P., Prat, A.

Kenison, J.E., Jhaveri, A., Li, Z., Khadse, N., Tjon, E., Tezza, S., Nowakowska, D., Plasencia, A., Stanton, V.P., Jr., Sherr, D.H., & Quintana, F.J. Tolerogenic nanoparticles suppress central nervous system inflammation.

Giovannoni F., Bosch I., Polonio M.C., Torti M.F., Wheeler M.A., Li Z., Romorini L., Rodriguez Varela M.S., Rothhammer V., Barroso A., Tjon E. C., Sanmarco L. M., Takenaka M.C, Modaresi S., Gutiérrez-Vázquez C., Ghabdan Zanluqui N., Barreto dos Santos N., Demarchi Munhoz C., Wang Z., Damonte E.B., Sherr D., Gehrke L., Schatzmann Peron J.P., Garcia C.G.

Wheeler M.A., Clark I.C., Tjon E.C., Li Z., Zandee S.E.J., Couturier C.P., Watson B.R., Scalisi G., Alkwai S., Rothhammer V., Rotem A., Heyman J.A., Thaploo S., Sanmarco L.M., Ragoussis J., Weitz D., Petrecca K., Moffitt J.R., Becher B., Antel J.P., Prat A.

Sanmarco, L. M., Wheeler, M. A., Gutiérrez-Vázquez, C., Polonio, C. M., Linnerbauer, M., Pinho-Ribeiro, F. A., Li, Z., Giovannoni, F., Batterman, K. V., Scalisi, G., Zandee, S., Heck, E. S., Alsuwailm, M., Rosene, D. L., Becher, B., Chiu, I. M., Prat, A.

Clark, I. C., Gutiérrez-Vázquez, C., Wheeler, M.A., Li, Z., Rothhammer, V., Linnerbauer, M., Sanmarco, L.M., Guo, L., Blain, M., Zandee, S., Chao, C.C., Batterman, K.V., Schwabenland, M., Lotfy, P., Tejeda-Velarde, A., Hewson, P., Manganeli Polonio, C., Shultis, M.W., Salem, Y., Tjon, E.C., Fonseca-Castro, P.H., Borucki, D.M., Alves de Lima, K., Plasencia, A., Abate, A.R., Rosene, D.L., Hodgetts, K.J., Prinz, M., Antel, J.P., Prat, A.

Sanmarco L.M., Chao C.C., Wang Y.C., Kenison J.E., Li Z., Rone J.M., Rejano-Gordillo C.M., Polonio C.M., Gutierrez-Vazquez C., Piester G., Plasencia A., Li L., Giovannoni F., Lee H.G., Faust Akl C., Wheeler M.A., Mascanfroni I., Jaronen M., Alsuwailm M., Hewson P., Yeste A., Andersen B.M., Franks D.G., Huang C.J., Ekwudo M., Tjon E.C., Rothhammer V., Takenaka M., de Lima K.A., Linnerbauer M., Guo L., Covacu R., Queva H., Fonseca-Castro P.H., Bladi M.A., Cox L.M., Hodgetts K.J., Hahn M.E., Mildner A., Korzenik J., Hauser R., Snapper S.B.

Clark I.C., Mudvari P., Thaploo S., Smith S., Abu-Laban M., Hamouda M., Theberge M., Shah S., Ko S.H., Pérez L., Bunis D.G., Lee J.S., Kilam D., Zakaria S., Choi S., Darko S., Henry A.R., Wheeler M.A., Hoh R., Butrus S., Deeks S.G., Quintana F.J., Douek D.C., Abate A.R.

Clark I.C., Wheeler M.A., Lee H.G., Li Z., Sanmarco L.M., Thaploo S., Polonio C.M., Shin S.W., Scalisi G., Henry A.R., Rone J.M., Giovannoni F., Charabati M., Akl C.F., Aleman D.M., Zandee S.E.J., Prat A., Douek D.C., Boritz E.A., Quintana F.J., Abate A.R.

Wheeler M.A., Clark I.C., Lee H.G., Li Z., Linnerbauer M., Rone J.M., Blain M., Akl C.F., Piester G., Giovannoni F., Charabati M., Lee J.H., Kye Y.C., Choi J., Sanmarco L.M., Srun L., Chung E.N., Flausino L.E., Andersen B.M., Rothhammer V., Yano H., Illouz T., Zandee S.E.J., Daniel C., Artis D., Prinz M., Abate A.R., Kuchroo V.K., Antel J.P., Prat A., Quintana F.J. Droplet-based forward genetic screening of astrocyte-microglia cross-talk.

Sanmarco LM, Rone JM, Polonio CM, Fernandez Lahore G, Giovannoni F, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Faust Akl C, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Stevens NA, Piester G, Chung EN, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ.

Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel J, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ.