Friendly Neighborhood Spider-Man was canceled after issue #24, part 2 of J. Michael Straczynski and Joe Quesada's controversial "One More Day" storyline.

[1] In March 2019 a new volume was launched by writer Tom Taylor and artist Juan Cabal and lasted 14 issues, ending in February 2020.

They talk, and Mary Jane shows Vanna Spider-Man's bloodied mask, thus proving her thoughts of him surviving were wrong.

Faced with the unbridled anger and hatred of protesting parents, as well as his own sense of responsibility for potentially endangering his students by revealing his secret identity in support of Iron Man's Pro-Registration movement, Peter decides to resign his station as science teacher in Midtown high.

Also of note is the inclusion of Miss Arrow, a nurse who falls in love with Flash Thompson and may be more than she seems: she is able to emit stingers from her wrist, much like Spider-Man himself.

Before after school programs are completed, Francis Klum returns as the new Mysterio and traps Spider-Man and the students and staff of Midtown High inside the building, within an impenetrable cloud of noxious gasses.

Inside, Spider-Man seeks out Francis Klum's Mysterio, as Flash Thompson and Miss Arrow help the remaining students escape the school.

Beck removes his helmet, revealing himself to be missing half of his head, a telltale reminder of his previous death, by suicide.

Deb has written a book titled “TWO FACED: How Spider-Man Ruined My Life.” The Vulture predicts Peter will show up and a battle is staged in medias res.

Meanwhile, Deb Whitman confesses to Betty Brant that the Daily Bugle pressured her and gave her money to write the scathing tell-all book, and apologizes.

Starting with the "Back In Black" storyline, Spider-Man now hides out under the guise of Ben Reilly and takes a job as Flash Thompson's assistant coach.

Revealing its true form, Spider-Man and Sandman were able to stop the creature moments before Floyd Baker was executed.