[6] Upon his return to Basel, his father became a shareholder of his former employer, who gave Fritz a leading position in the business.

It was a common practice in Switzerland for married couples to hyphenate the name to incorporate both surnames, so from this point he was often referred to as Fritz Hoffmann-La Roche.

Hoffman remarried, to divorcée Elisabeth von der Mühll, also of the Daig (1882–1970).

[9] She was the second child of Count Andreas Razumovsky and Princess Katharina Nikolajevna Sayn-Wittgenstein, who fled Russia in 1918 after the October Revolution.

He also built up international contacts for raw materials and product sales, and supported research.