Frozen Run is a tributary of Hemlock Creek in Columbia County, Pennsylvania, in the United States.

A. Joseph Armstrong describes Frozen Run as "pretty mundane" in his book Trout Unlimited's Guide to Pennsylvania Limestone Streams.

In Frosty Valley, the stream turns east and flows for a few miles before reaching its confluence with Hemlock Creek near the community of Buckhorn.

[1] Frozen Run joins Hemlock Creek 2.26 miles (3.64 km) upstream of its mouth.

[4] Parts of Frozen Run and several of its unnamed tributaries are considered by the Pennsylvania Department of Environmental Protection to be impaired by siltation due to agriculture.

[3] Areas that are hazardous during floods are largely undeveloped in the watershed of Frozen Run.