Fundación Biblioteca Rafael Hernández Colón is located on two historic buildings, both adjacent to each other, both facing west on Calle Mayor.

In 1896, Gaspar Bonnín y Miró, a businessman from Mallorca, Spain, bought the property, as the Hospital moved to a new and more spacious building elsewhere in the city.

[2] The structure for the Ponce District Courthouse, and still standing, was designed by Manuel Víctor Domenech, an architect from Isabela, Puerto Rico, in the neoclassical style.

In addition to its historical archives, the facilities also include an amphitheater, a Sala de la Historia Constitucional (constitutional history hall), a children's library and a museum.

[10] It also contains details of Museo del Autonomismo Puertorriqueño, a small museum located in Barrio Segundo that showcases the political history of Puerto Rico with an emphasis on the contributions made by the municipality of Ponce and its residents.