884380885ENSG00000255398ENSMUSG00000045502P49019Q9EP66NM_006018NM_030701NP_006009NP_109626Hydroxycarboxylic acid receptor 3 (HCA3), also known as niacin receptor 2 (NIACR2) and GPR109B,[5] is a protein which in humans is encoded by the HCAR3 gene.

[6][7] HCA3, like the other hydroxycarboxylic acid receptors HCA1 and HCA2, is a Gi/o-coupled G protein-coupled receptor (GPCR).

[5][8] The primary endogenous agonists of HCA3 are 3-hydroxyoctanoic acid and kynurenic acid.

[5][8][9] HCA3 is also a low-affinity biomolecular target for niacin (aka nicotinic acid).

[10] This article on a gene on human chromosome 12 is a stub.