[5] The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina.

The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state.

[5] Defects in this gene may be a cause of X-linked retinitis pigmentosa.

[5] This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on the human X chromosome and/or its associated protein is a stub.