[5][6][7] Synuclein-gamma is a member of the synuclein family of proteins, which are believed to be involved in the pathogenesis of neurodegenerative diseases.

High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

[8] It is also detected in the brain, ovarian tumors, and in the olfactory epithelium.

A change in the expression of gamma-synuclein has been observed in the retina of patients with Alzheimer's disease.

The normal cellular function of gamma-synuclein remains unknown.