Once in Hogansville, SR 100 turns north concurrent with US 29/SR 14 for a short distance before continuing northwest alone.

As SR 100 moves toward Tallapoosa, it crosses I-20, where it is the first eastbound exit in the state for that highway.

South of Cedartown, SR 100 turns west following US 278 for a brief distance before resuming a northwestern path.

It begins in the southern portion of Tallapoosa, at an intersection with the SR 100 mainline (Alewine Avenue).

Just past Golf Course Road, the spur curves to the north-northeast and meets its northern terminus, an intersection with US 78/SR 8 (East Atlanta Street) in the eastern part of town.