The route begins at an intersection with SR 135 in Petross in east-central Montgomery County.

It heads northeast into the center of Vidalia to an intersection with US 280/SR 15/SR 29/SR 30.

It continues to the northeast until it meets its eastern terminus at an intersection with US 1/SR 4 north of downtown Lyons (but within the northern part of the city limits).

[1] A very brief portion of SR 130 in Vidalia is the only part included in the National Highway System (NHS), a system of roadways important to the nation's economy, defense, and mobility.

[2] The portion within the NHS is from the southernmost US 280 intersection to the northern city limits.