Georgios Karaiskakis (Greek: Γεώργιος Καραϊσκάκης) is a municipality in the regional unit of Arta, Greece, named after Georgios Karaiskakis, a leader of the Greek War of Independence.

The seat of the municipality is in Ano Kalentini.

[2] The present municipality Georgios Karaiskakis was formed at the 2011 local government reform by the merger of the following 3 former municipalities, that became municipal units:[2] The municipality has an area of 463.889 km2, the municipal unit 174.179 km2.

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