[3][4] The second International Hygiene Exhibition was held in 1930-31, in a building erected west of the Großer Garten park according to plans designed by Wilhelm Kreis, which became the museum's permanent home.

Various Nazi government offices relocated to the museum between 1933 and 1941,[6] and the German Labour Front's Reichsberufswettkampf (National Vocational Competition) was held there in 1944.

It produced a wide range of educational material, including short films on subjects such as smoking, breastfeeding, sexually transmitted diseases and teenage pregnancy.

[11] The museum owns an extensive collection of around 45,000 items documenting the public promotion of bodily awareness and healthy day-to-day behaviour, mostly from the early 20th century onwards.

The museum also organises scientific and cultural events, including talks, meetings, debates, readings, and concerts.