British studio Foursfield developed a version for Commodore 64, Amiga, Atari ST, Amstrad CPC and ZX Spectrum, which also got ported to the MSX by New Frontier.

The non-DOS versions were praised for the graphics and audio, but criticized for long loading times, disk swapping, and the final level.

[1][2][3] The DOS version of the game begins with the Ghostbusters battling the ghosts of the Scoleri brothers in a courtroom, as in the film.

The player can also collect slime samples from an abandoned underground train tunnel, but must avoid Slimer ghosts in the process.

The player must earn $55,000 to take control of the Statue of Liberty, which is used to reach an art museum, where the Ghostbusters battle Vigo.

[1] The other computer versions – Commodore 64, Amiga, Atari ST, Amstrad CPC, ZX Spectrum and MSX – feature three distinct levels based on scenes from the film.

[4][5][2][3][6] In the first level, Ray Stantz is lowered into a subway tunnel to collect slime, while using three different weapons to deter various spirits.

[11][14][3] The Amiga and ZX Spectrum versions received a budget re-release in late 1991, published by The Hit Squad.

Wilson praised the graphics, the Statue of Liberty level, and the digitized voice tracks, and called the game "well-designed and easily learned."

[9] Mark Higham of ST Format considered the gameplay tedious and worse than the original Ghostbusters game.

"[20] Amiga User International stated that none of the levels were particularly addictive, and opined that the game "offers pretty poor value for money" considering that the player's "only motivation is to see the following stage".

"[27] The following year, Amiga Power's Stuart Campbell reviewed the re-release and criticized the gameplay as "lame and uninspired".