Giant condyloma acuminatum (also known as a Buschke–Löwenstein tumor[1]) is a rare cutaneous condition characterized by an aggressive, wart-like growth that is a verrucous carcinoma.

[3] Due to their size, these tumors can be locally invasive and destructive.

Owing to their impressive growth patterns, Buschke-Löwenstein tumors displace and destroy adjacent structures from compression.

[4] In general these masses are benign, but the potential for malignant transformation to squamous cell carcinoma exists in the long term, as does the rare risk for metastasis.

[6][8][7] Although penile sparing is the goal, total penectomy may be required.