Through its hospital, clinics and greater Minnesota locations, Gillette treats patients with brain, bone and movement conditions needing specialized expertise.

Originally, it was situated in a ward inside City and County Hospital of St. Paul, but in 1911 it outgrew that limited space and moved into its own facilities in Phalen Park.

[1] Gillette Children's treats patients who have some of the rarest and most complex conditions in pediatric medicine, including cerebral palsy, scoliosis, plagiocephaly, brain and spinal cord injury, epilepsy and seizures, torticollis, hydrocephalus, craniosynostosis, spina bifida, muscular dystrophy, cleft lip and palate, limb-length discrepancy, spinal muscular atrophy and osteogenesis imperfecta.

Gillette provides inpatient and outpatient rehabilitation therapy to help patients mitigate the effects of disabilities and to return function following serious injury or complex surgery.

To help make it easier for families to coordinate multiple appointments, Gillette organizes care around the child's condition.