Scarlatti's performance caught the eye of Maserati who decided to hire him for the 1957 Formula One season.

Scarlatti's best results were at the Pescara Grand Prix, where he narrowly missed out on the points-scoring positions when his Maserati 250F was overtaken in the latter stages by Stuart Lewis-Evans[2] and the Italian Grand Prix, where he finished fifth, sharing the car with Harry Schell.

In 1957 Scarlatti competed at the 24 Hours of Le Mans, sharing a Maserati with Joakim Bonnier.

Bonnier and Scarlatti were forced to retire after 7 hours due to a clutch problem.

In 1961 Scarlatti and Lorenzo Bandini won the 4 Hours of Pescara on a Ferrari 250 Testa Rossa.