Gisela of Burgundy (c.  955 – 21 July 1007), a member of the royal Elder House of Welf, was Duchess of Bavaria from about 972 to 976 and again from 985 to 995, by her marriage with Duke Henry the Wrangler.

In 951 Otto married Conrad's sister Saint Adelaide of Burgundy, the widow of Hugo's son King Lothair II of Italy.

Gisela with her young son Henry II sought refuge with Bishop Abraham of Freising; during her husband's imprisonment, she resided in Merseburg.

He again tried to snatch the crown from the minor successor Otto III, however, with the intervention by Dowager Empress Theophanu and her predecessor, Gisela's aunt Adelaide of Burgundy, he finally submitted in 985 and regained his Bavarian duchy.

Her daughter Gisela of Hungary donated an opulent burial cross, known as Giselakreuz, which today is part of the collections at the Munich Residenz treasury.