He was selected by the Kansas City Chiefs with the fifth overall pick in the 2008 NFL draft, and played for the San Francisco 49ers later in his career as well.

As a senior, he missed three games due to an ankle injury, and finished the season with 43 tackles, two sacks and one forced fumble.

He was among LSU's 4-player rotation at defensive tackle which included Claude Wroten and Kyle Williams.

He finished the season as the Tigers' third-leading tackler with 64 stops, including 8.5 for losses and three sacks.

He was a key component in LSU’s drive to the BCS national title despite playing the second half of the season with knee and tailbone injuries.

[11] Prior to the draft some NFL teams expressed concern over a lingering stress fracture Dorsey sustained in 2006.

At the NFL Combine, Dorsey spent nearly ten hours getting examined at an Indianapolis hospital.

[13] Dorsey was selected by the Kansas City Chiefs in the first round with the fifth overall pick in the 2008 NFL draft.

[17] On November 8, he recorded his first career sack against San Diego Chargers quarterback Philip Rivers.