ʔ ⟨Majuscule: Ɂ, Minuscule: ɂ⟩, called glottal stop, is an alphabetic letter in some Latin alphabets, most notably in several languages of Canada where it indicates a glottal stop sound.

The letter derives graphically from use of the apostrophe ⟨ʼ⟩ or the symbol ʾ for glottal stop.Where ⟨ʔ⟩ is not available, not being in the basic Latin alphabet, it is sometimes replaced by a question mark ⟨?⟩, which is its official representation in the SAMPA transcription scheme.

In Unicode, four graphic variants of the glottal stop letter are available.

These include the 9-shaped modifier letter apostrophe, ⟨ʼ⟩, which is probably the most common (and the direct ancestor of ⟨ʔ⟩), the 6-shaped ʻokina of Hawaiian, ⟨ʻ⟩, and the straight-apostrophe shaped saltillo of many languages of Mexico, which has the case forms ⟨Ꞌ ꞌ⟩.

Then, in version 5.0 (2006), it was decided to separate the cased and caseless usages by adding a dedicated lowercase letter.