[3] After oral ingestion of 600 mg of glycyrrhizin the metabolite appeared in urine after 1.5 to 14 hours.

[4] Licorice extract (glycyrrhizin) is sold in the United States as a liquid, paste, or spray-dried powder.

[4] When in specified amounts, it is approved for use as a flavor and aroma in manufactured foods, beverages, candies, dietary supplements, and seasonings.

[5] The most widely reported side effect of glycyrrhizin use via consumption of black liquorice is reduction of blood potassium levels, which can affect body fluid balance and function of nerves.

[6][7] Chronic consumption of black licorice, even in moderate amounts, is associated with an increase in blood pressure,[7] may cause irregular heart rhythm, and may have adverse interactions with prescription drugs.