Gradient enhanced NMR spectroscopy

Gradient enhanced NMR is a method for obtaining high resolution nuclear magnetic resonance spectra without the need for phase cycling.

Gradient methodology is used extensively for two purposes, either rephasing (selection) or dephasing (elimination) of a particular magnetization transfer pathway.

It includes the application of magnetic field gradient pulses to select specific coherences.

By using actively shielded gradients, a gradient pulse is applied during the evolution period of the selected coherence to dephase the transverse magnetization and another gradient pulse refocuses the desired coherences remaining during the acquisition period.

*Ralph E. Hurd, Gradient-Enhanced Spectroscopy, Journal of magnetic resonance.