In late 1950s, during the Cuban Revolution, Che Guevara established his first guerrilla camp near the town.

[4] Located on a plain between Zaza Reservoir and the Caribbean Coast, Guasimal is a rural village surrounded by some scattered hillocks and a forest area.

It is 11 km from Paredes, 17 from Entronque Guasimal, 20 from Tunas de Zaza, 23 from Banao, 27 from Sancti Spíritus, 36 from La Sierpe and 74 from Trinidad.

[5] The village is served by a railway station on the Sancti Spíritus-Tunas de Zaza line.

Entronque Guasimal, 17 km north of it, is crossed in the middle by the state highway "Circuito Sur" (CS).