Guatemala competed at the 2011 Pan American Games in Guadalajara, Mexico from October 14 to 30, 2011.

Guatemala qualified a paleta leather pairs 30m fronton (2 athletes) in the sports debut at the Pan American Games.

Guatemala qualified a full team of 4 athletes (2 men and 2 women).

Colombia has qualified a men's and women's team in the roller skating competition.

Men Women Guatemala qualified a full squash team.