Panama competed at the 2011 Pan American Games in Guadalajara, Mexico from October 14 to 30, 2011, but its athletics team, including defending gold medalist Irving Saladino, did not compete because the Panama athletics association has had issues with the Panama Olympic Committee.

[2] Panama qualified a baseball team of twenty-three athletes to participate.

Seventh place match Panama qualified two male athletes in the bowling competition.

Individual Pairs Men Jumping Individual Women Panama qualified one athlete in the 61 kg women's category.

Men Women Panama qualified one athlete in the 84 kg men's freestyle category, one athlete in the 74 kg men's Greco-Roman category, and one athlete in the 72 kg women's category.